Once you complete the Second Helpings main quest in Flatwoods, you’ll successfully register as a certified Responder. Your next step is to investigate an emergency message being broadcast from the Responder HQ, which is located at Morgantown Airport. In the Fallout 76 Final Departure main quest you’ll learn more about the Scorched, as well as the terrible cause of their condition.
How to Complete the Fallout 76 Final Departure Main Quest
Once you receive the emergency message on the Responder registration kiosk in Flatwoods, you should automatically start the Fallout 76 Final Departure main quest. While First Contact, Thirst Things First, and Second Helpings have been relatively sedate, things are about to change dramatically. Your first objective is to make the long trek from Flatwoods along Interstate 59 to Morgantown Airport. As you draw closer to the Airport, you’ll pick up a Responder Emergency Signal on your Pip-Boy radio.
Once you arrive at the Airport you will see a large number of creepy petrified remains standing around outside. These don’t pose a direct threat, but if you attack them or simply stand too close, the remains will collapse and release a miasma of radiation which will linger for a short while. Head past the harrowing remains and enter the airport Terminal. Both outside and inside you will find yourself beset by Scorched; ghoul-like creatures with burnt red skin pockmarked with glowing green growths. The Scorched are one of the key enemies of Fallout 76, and you’re about to learn a lot more about them.
Make your way upstairs to the quest marker where you’ll find one of the Overseer’s caches. Finding this cache also counts towards the Overseer’s Mission side quest. Listen to the Overseer’s Log holotape which you find inside the cache and you’ll hear the Overseer’s observations about the Scorched. You can also access a Responder terminal to learn more about their own dealings with the Scorched. It seems that they were attempting to develop an inoculation.
Head back outside and make your way eastwards to the corrugated iron hangars. One of these will be marked with “Medical,” with a Paramedic symbol. Inside, on the second floor, you can access a terminal. Read the “Innoculation Project Announcement,” topic to complete the Final Departure quest. Completing the quest will reward you with Patrolman’s Sunglasses and the Somerset Special (a modded .44 pistol). You’ll also receive random ammo and a random aid item. This will also give you the next main quest; An Ounce of Prevention. Note that while you’re in Morgantown Airport, you can start the Safe for Work and Tentative Plans side quests.